A novel and efficient method for the olefination of carbonyl compounds with Grignard reagents in the presence of diethyl phosphite.
نویسندگان
چکیده
The widely available carbonyl compounds react with Grignard reagents in the presence of diethyl phosphite to give the corresponding olefins in good to excellent yields: A range of conjugated dienes, terminal olefins, multisubstituted-alkenes and conjugated enynes could be readily obtained by the method in mild conditions.
منابع مشابه
A novel ketone olefination via organozinc reagents in the presence of diphenyl phosphite.
Carbonyl compounds react with organozinc reagents in the presence of diphenyl phosphite to give the corresponding olefins. A variety of 1,3-dienes and unsaturated esters were obtained in moderate to excellent yields under mild conditions.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 8 10 شماره
صفحات -
تاریخ انتشار 2010